CBD: collateral effects?
The first hemp cultivation dates to 6000 years ago in China. Hemp is a plant that contains more than 400 natural compounds, among which we find the two main groups of molecules with active properties: terpenes and cannabinoids. The CBD belongs to the latter compounds.
Cannabinoids are molecules capable of interacting with the functions of our nervous system. The hemp plant biosynthesizes more than 60 cannabinoids that differ from one another in the processes of interaction with our body and in their specific molecular structure. Among the best known we find THC, CBD and CBG.
Cannabidiol, or CBD, is one of the most abundant cannabinoid in cannabis. It has been widely demonstrated that this molecule has different therapeutic properties, including the ability to relax the body. Although it acts on our body offering important benefits, CBD has no psychoactive properties like its closest relative, THC. We must not therefore confuse the action of these two cannabinoids.
CAN CBD GET YOU HIGH?
No. After taking CBD you will not notice any psychoactive effects. In other words, CBD oil does not affect mood, conscience or mental faculties in the slightest.
IS THE CBD SUITABLE FOR MY NEEDS?
CBD oil is an increasingly popular dietary supplement due to its beneficial properties for our health. It can be used like any other effective natural product to improve people's quality of life. However, as often happens with many other natural compounds, the body's responses to CBD can vary from individual to individual. Its ability to improve a person's well-being or to alleviate certain health problems can only be understood once he has been tried. To learn more about this interesting topic, we invite you to consult information from unbiased sources without any commercial interest, such as Wikipedia or other sites with reliable medical information. You can also follow the latest clinical research published on our website.
Thanks to numerous studies on dosage and methods of application of CBD, no side effects related to its consumption have been detected up to now.
HOW TO USE THE CBD
Regardless of how it is taken, the most recommended CBD oil dosage is 3-4 drops three times a day. According to a recent study, our body can tolerate up to 160mg / day of CBD.
The CBD can be taken in the same way as any other health beneficial supplement. The most common applications are oral and cutaneous, through which we can absorb all its biological compounds.
* The most practical and simple method of taking CBD is sublingual. The tissue present beneath the tongue, in fact, is rich in capillaries that allow a rapid diffusion of cannabidiol into the bloodstream. The CBD has a rather pleasant taste. If you are afraid of taking too much at once, apply a drop of oil to the tip of a clean (essential!) finger and lick it. You can also apply a few drops of oil on permeable foods, such as a piece of bread or a biscuit.
* If you have any dermatological problems, you can apply CBD oil directly to the area of irritated skin, but we recommend diluting our concentrated oil with neutral lotions, in order to increase the contact surface and reduce any leakage.
PUBLIC HEALTH CARE COVER THE CBD OIL?
Unfortunately, not! CBD oil is not a drug, but a food supplement. Public healthcare does not cover many other products that are potentially beneficial to our health, such as massages, spas, organic foods, etc. Normally, healthcare covers the costs of a therapy when the patient has already shown the disease. However, we know how important it is to prevent diseases to improve and increase the resistance of our body. The extra expenses for our health are always money well spent.
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HOW DOES THE CBD WORK?
Numerous receptors are present in our nervous system. Receptors are like mobile telephony antennas that receive and transmit signals. Just as a repeater receives a specific electromagnetic wave as a signal, receptors also receive specific molecules to receive and transmit certain messages.
One of these systems composed of different receptors is the endocannabinoid system (SEC). The SEC receptors are distributed in the brain and peripheral nervous system (spinal cord and nerves). In the brain, these receptors are mainly present in the areas responsible for perception, concentration, memory and movement. Therefore the SEC is involved in the regulation of many physiological processes, including those related to feelings of pain, mood and appetite. Furthermore, the SEC is also part of the neural system activated by exercise. For example, the so-called "Runner's Loss" is caused by the action of the endocannabinoid system.
The receptors that make up the SEC are: CB1 and CB2, 5-HT1A, μ and δ. These receptors bind to cannabinoids produced by our nervous system, endorphins. One of the most important endorphins that transmit signals to the SEC is 2- arachidonoyl glycerol (2-AG). This molecule binds to the CB1 and CB2 receptors. Also, cannabidiol CBD, binds to these receptors, generating the same effects as 2- AG.
The CBD also binds to the same receptors as the psychoactive cannabinoid, THC, but the effects it generates are opposite. If on the one hand THC accelerates the nervous system, on the other the CBD slows it down.
According to numerous researches, CBD has anti-spasmodic, anti-psychotic, anti- convulsant and neuroprotective properties. Therefore, the application of a CBD oil can be very effective for relaxing the muscles and the body in general. CBD also can relieve daily stress, making the nervous system more resistant to external stimuli.
BIOLOGY AND CHEMISTRY OF THE CBD
Cannabis sativa plants that grow wild in the woods produce numerous organic compounds, such as THC and CBD. Exactly like many other plant species grown today by humans, even Cannabis has been selected and hybridized with the aim of obtaining specific molecules with a medium-high concentrations, for the most different purposes. These hybridization processes have transformed the original plant, giving rise to different varieties of Cannabis with different qualities (think of the Brussels sprouts and cauliflower artificially produced from the wild brassica). In these last decades, man has had as main objective to create variety of "Cannabis" with a high THC content, neglecting all the other potentially beneficial compounds. On the other hand, however, the varieties of "hemp" have been selected for years with the aim of enhancing their quality in the industrial field and to increase their concentrations of CBD, to the detriment of those of THC. CBD and THC are two cannabinoids closely related to the terpenoids of plant origin such as menthol, camphor and curcuminoids, produced from turmeric and mustard seeds. The terpenoids belong to a large class of organic molecules widely used in traditional cuisine for their aromatic qualities. However, they also play a leading role in traditional herbal natural remedies. THC and CBD are produced through the same biosynthesis processes. In other words, they are born from the same precursor molecule, or from cannabigerolic acid or CBGA. When this precursor is present, an enzyme, THCA synthase, metabolizes and converts the CBGA into THCA, which in turn, after decarboxylation, converts to THC.